Day 1
WEDNESDAY October 25
12:30 – 14:30 ESPT Executive Board meeting – Closed Meeting
15:00 – 15:45 Meeting with ESPT National Representatives – Closed Meeting
16:00 – 17:00 ESPT General Assembly
13:00 – 18:00 Pre – Registration
18:00 – 19:30 OPENING RECEPTION at the congress venue DGI-Byen
Day 2
THURSDAY October 26
- 07.30 Registrations open
- 08:45 Opening and Welcome – Lona Louring Christrup
Welcome – Danish Ministry of Health
Welcome on behalf of ESPT – Ann Daly
- SESSION: PGx CLINICAL IMPLEMENTATION
Chairs: Lona Christrup & Ann Daly
09:00 A historic overview of pharmacogenetics: Kim Brosen’s perspective – Kim Brøsen
09:30 Implementing pharmacogenomic panel testing in Europe: experiences from the U-PGx PREPARE study – Jesse Swen
09:55 Pharmacogenomics beyond single common genetic variants: the way forward – Magnus Ingelman-Sundberg
10:20 – 10:50 COFFEE BREAK
- SESSION: PSYCHIATRY
Chairs: Sanja Stankovic & Michael Asger Andersen
10:50 PGx-guided precision dosing of antidepressants – all settled? – Espen Molden
11:15 Applying PGx in Psychiatry: Taking things personally – Daniel Mueller
11.40 Real World Pharmacogenetic experience from a Canadian perspective – Ruslan Dorfman
12:05 Global Diversity Array with enhanced PGx as a method for panel PGx testing: results of a validation study with samples from the PREPARE study – Sylvia Klomp
12:30 Cost-effectiveness of pharmacogenomic-guided treatment: results from a microsimulation model for major depression – Shahzad Ghanbarian
12:45 – 13:45 LUNCH / POSTER VIEWING /BOOTH VISITS
- SESSION: ONCOLOGY
Chairs: Mikko Niemi & Niels Westergaard
13:45 DPYD pharmacogenetics: the long and winding road to precision dosing of fluoropyrimidines – Erika Cecchin
14:10 Addressing phenoconversion with the Geneva phenotyping cocktail: clinical experience – Caroline Samer
14:35 Drug transporters and novel biomarkers in chemotherapy-induced peripheral neuropathy – Tore Bjerregaard Stage
15:00 Clinical opportunities for germline pharmacogenetics and management of drug-drug interactions in patients with advanced solid cancers – Vicky Pratt
15.25 Germline variants are associated with clinical outcomes and pharmacokinetics in patients with ALK+ NSCLC treated with alectinib – Niels Heersche
15:40 – 16:10 TEA BREAK
- SESSION: ctDNA
Chairs: Ron van Schaik & Vita Dolzan
16:10 Liquid Biopsy: From Discovery to Clinical Implementation – Klaus Pantel (KEYNOTE LECTURE)
16:40 Circulating Tumor DNA for Minimal Residual Disease Detection and Risk-Stratified Recurrence Surveillance – Claus Lindbjerg Andersen
17:05 The power of circulating tumor cells in immuno-oncology- Catherine Alix Panabieres
- 17:30 CLOSURE
- 20:00 CONGRESS DINNER
Day 3
FRIDAY October 27
- SESSION: PGx CHALLENGES
Chairs: Ron van Schaik & Kim Dahlhoff
08:45 Pharmacogenomics of Adverse Drug Reactions – Sir Munir Pirmohamed KEYNOTE LECTURE
09:15 The future of PGx testing; lessons from the 100,000 Genomes project – Matt Brown KEYNOTE LECTURE
09:40 Pharmacogenomics with Rural and Indigenous Communities – Erica Woodahl
10:05 – 10:35 COFFEE BREAK
- SESSION: CARDIOLOGY
Chairs: Adrian Llerena & Vangelis Manolopoulos
10:35 Impact of Implementing CYP2C19 Genotype Guided Antiplatelet Treatment in Clinical practice – Wout van den Broek
11:00 Statin pharmacogenetics – clinical relevance and implementation – Mikko Niemi
11:25 Pharmaco(epi)genomics of oral anticoagulation therapy with DOACs – Vangelis Manolopoulos
11:50 Pharmacogenetics in clinical practice, experience and expectations of pharmacogenetic tests – Marieke Coenen
12:15 Exploring the Genetic Basis of Dyspnea in Individuals Treated with Ticagrelor – Marc-Olivier Pilon
12:30 – 13:30 LUNCH / POSTER VIEWING /BOOTH VISITS
- SESSION: PERSONALISING DRUG TREATMENT
Chairs: Vita Dolzan & Morton Balzer
13:30 Cocktail approach of probe drugs applying GWAS: Further variants of relevance? – Ingolf Cascorbi
13:55 Clinical scenarios where point of care pharmacogenetic testing improves outcome – William (Bill) Newman
14:20 OPRA (Oncology Precision Project Aarhus); Pharmacogenomically guided treatment for cancer patients – Britt Elmedal Laursen
14:45 Identification of DPYD copy number variation in Finnish population using high-throughput next generation sequencing – Sofia Khan
15:00- 15:30 COFFEE BREAK
- SESSION: FOCUS ON THE FUTURE
Chairs: Csilla Sipeky & Jon Thor Traerup Andersen
15:30 Progress at the Danish National Genome Center – Peter Johansen
15:55 Using NGS for PGx – Robert Akkers
16:20 Clinical Pharmacogenetics Implementation in Spanish Health Service (MedeA, IMPaCTm BiofRAM) – Adrian Llerena
- 16:45 POSTER PRIZE
- 17:00 CLOSURE
Day 4
SATURDAY October 28
Discussion Forum: How to move forward with implementing PGx?
- 9.30 – 10.00 WELCOME COFFEE
- 10:00 – 10:45 PANEL SESSION 1: IMPLEMENTATION
SHORT INTRO: Reflection on implementation of PGx in UK
– Professor Sir Munir Pirmohamed, MD/PhD
– Erika Cecchin – Italy (Oncology)
– Britt Elmedah Laursen – Denmark (Oncology)
– Adrian Llerena – Spain (PGx-implementation)
– Daniel Mueller – Canada (Psychiatry)
– William (Bill) Newman – England (Clinical Genetics)
– Mikko Niemi – Finland (general PGx services)
– Jesse Swen – The Netherlands (PGx-services)
- 10:45 – 11:15 PANEL SESSION 2: INDUSTRY VIEW
SHORT INTRO: PGx in the near future: a laboratory perspective
– Daniel Langhoff – Director Eurofins Genomics, Denmark
– Ruslan Dorfman – Pillcheck Canada
– Tiffany Morris – Illumina
– Vicky Pratt – AGENA Bioscience
– Dominique Dewolf – Thermo Fisher Scientific
- 11:15 – 11:45 PANEL SESSION 3: PGx RESEARCH
SHORT INTRO: Which (additional) research is needed?
– Magnus Ingelman-Sundberg – Karolinska Instituten, Sweden
– Matt Brown – Biobank – Genomics England
– Kim Brosen, Clinical Pharmacology – Denmark
– Ingolf Cascorbi – Clinical Pharmacology – Germany
- 11.45 CLOSURE + Announcement 2025 ESPT venue – Ann Daly